An ad hoc network is a collection of wireless mobile nodes that are capable of forming a cooperative agreement (network) between themselves without requiring any centralized control function. Due to their non-reliance on fixed infrastructure, ad hoc networks are gaining popularity in several networking applications including, military, rescue operations and meetings and conventions. Generally, protocols used at medium access and physical layers of ad hoc networks are similar to those used in infrastructure based wireless networks. It is a common practise in infrastructure based wireless networks to use pre-data exchange of control information to eliminate the "hidden terminal" problem. Although the use of pre-data exchange of control information introduces the "exposed terminals", it has been shown that throughput performance of infrastructure networks generally improves with use of such mechanisms. However, ad hoc networks topologies differ signifcantly from those of access point based (infrastructure) wireless networks, hence the effect of hidden and exposed terminals in ad hoc networks is different than in infrastructure based networks. In this paper we show, through analytical studies and simulations, that exposed terminal problem dominates in ad hoc networks, and therefore, contrary to some previously published results, the use of RTS/CTS handshake may be detrimental to the network's throughput performance.